Maltese poodle dog scratching itself in a muddy outdoor area

How Essential Amino Acids can Treat Canine Superficial Necrolytic Dermatitis

Canine Superficial Necrolytic Dermatitis, is a rare skin condition affecting dogs and It leads to painful skin lesions, often associated with underlying liver disease or metabolic disturbances.

Research has proven that the use of Essential Amino Acids can aid in the treatment of Canine Superficial Necrolytic Dermatitis by repairing skin, reducing inflammation, and improving metabolic function.

With THRIVE Daily freeform amino acid supplements, your dog can fully absorb and utilize the amino acids they need.

What Is Canine Superficial Necrolytic Dermatitis?

Canine Superficial Necrolytic Dermatitis (SND), also known as hepatocutaneous syndrome, is a rare yet serious condition affecting dogs. It manifests in dogs as thick, crusty lesions primarily around the paws, muzzle, and genital areas. The lesions are painful and can hinder the dog’s mobility and quality of life. The underlying cause of SND is often amino acid deficiency due to liver dysfunction or other metabolic issues.


Without intervention, dogs diagnosed with SND typically have a poor prognosis, with survival rates averaging between 6 to 12 months. Standard treatment options include amino acid infusions and dietary adjustments. By focusing on essential amino acids, pet owners can improve their dog’s condition and potentially extend their pet’s life based on the study by Jaffey et al.

A dog putting its paws on the doctor

Study: Successful Long-Term Management of SND Using Amino Acids

In 2020, a case study published by Frontiers in Veterinary Science, Jaffey et al. detailed the successful management of a 10-year-old Bichon Frise diagnosed with Canine Superficial Necrolytic Dermatitis. The dog, suffering from painful skin lesions and metabolic issues, was treated with intravenous amino acid infusions and a nutritionally balanced, home-cooked diet rich in high-quality protein and essential amino acids. Over time, the frequency of amino acid infusions was reduced from every 2-3 weeks to once every 10-12 weeks, thanks to the positive effects of the diet modification. This case highlighted the importance of a customized diet tailored to the dog’s specific nutritional needs, emphasizing the critical role of amino acids in treating SND.

How Essential Amino Acids Aid in Treatment

Essential amino acids are the building blocks of protein that the body cannot produce on its own and must obtain through diet or supplementation. For dogs with Canine Superficial Necrolytic Dermatitis, amino acids play a vital role in repairing skin, reducing inflammation, and improving metabolic function.

Some of the key amino acids include Lysine, Leucine, Valine, and Tryptophan. These amino acids not only support the skin’s repair mechanisms but also help regulate liver function, which is often compromised in dogs suffering from SND.

Benefits of Amino Acid Therapy in SND Treatment

Incorporating amino acid therapy in the treatment of Canine Superficial Necrolytic Dermatitis provides several benefits:

  • Skin Healing: Amino acids such as lysine and leucine help rebuild damaged skin and improve the texture of the dog's paw pads and muzzle.
  • Reduced Inflammation: Essential amino acids work to reduce swelling and pain, making dogs more comfortable and mobile.
  • Improved Liver Function: Since liver dysfunction often underlies SND, boosting amino acids in the dog's diet can aid in the liver's ability to metabolize nutrients effectively.
  • Extended Time Between Treatments: As seen in the above case, the use of essential amino acids decreased the frequency of painful intravenous amino acid infusions from once every 2-3 weeks to once every 10-12 weeks.

Dietary Modifications and Amino Acids in Canine SND Treatment

Dietary changes play a critical role in managing Canine Superficial Necrolytic Dermatitis. In Jaffey et al.'s research, the 10-year-old Bichon Frise with SND showed dramatic improvement after switching to a high-protein, nutritionally balanced home-cooked diet rich in essential amino acids. The diet included:

  • Cooked chicken breast
  • Cooked eggs (a great source of amino acids)
  • Sweet potatoes for carbohydrates
  • Omega-3 supplements

Incorporating high-quality protein sources ensures that the dog receives enough amino acids for proper skin and metabolic function. Additionally, removing processed foods and focusing on whole, nutrient-rich ingredients further enhances the healing process.


A bowl with dog food, dog treats and toys on a wooden floor.

Essential Amino Acids to Focus on for SND

To optimize the treatment of Canine Superficial Necrolytic Dermatitis, it’s essential to focus on certain amino acids that have proven benefits for skin health and metabolic function. Here are the top amino acids to include:

  • Lysine: Promotes collagen formation, which is vital for skin repair.
  • Leucine: Supports muscle protein synthesis and enhances overall healing.
  • Valine: Helps reduce skin inflammation and speeds up recovery.
  • Tryptophan: Regulates serotonin levels, improving mood and reducing stress in affected dogs.

Practical Tips for Incorporating Essential Amino Acids in a Dog's Diet

Here are some simple ways to ensure your dog gets enough essential amino acids:

  • Cook high-protein meals: Focus on foods like chicken, turkey, eggs, and lean beef.
  • Incorporate amino acid supplements: Consult with a veterinarian to find the right amino acid supplements, such as omega-3 fatty acids and zinc.
  • Avoid raw eggs: While eggs are a great source of amino acids, always cook them to avoid nutritional imbalances and bacterial contamination.

Following these tips can help ensure your dog’s diet is rich in the amino acids needed to manage Canine Superficial Necrolytic Dermatitis effectively.

How THRIVE Daily Can Support Dogs with Canine Superficial Necrolytic Dermatitis

When it comes to treating Canine Superficial Necrolytic Dermatitis, ensuring your dog receives essential nutrients in the most absorbable form is key. THRIVE Daily, a freeform amino acid supplement, offers superior bioavailability compared to traditional supplements, meaning your dog can fully absorb and utilize the amino acids it needs to heal. Since SND is linked to amino acid deficiencies, THRIVE Daily ensures that critical amino acids like lysine and valine are delivered directly to the body, promoting skin repair, reducing inflammation, and improving overall metabolic function. By integrating THRIVE Daily into your dog’s routine, you can support more effective treatment and management of SND, enhancing your pet's quality of life.

The Importance of Amino Acids for Canine Health

Essential amino acids are vital for dogs suffering from Canine Superficial Necrolytic Dermatitis. Through targeted amino acid therapy and dietary modifications, pet owners can provide relief from painful skin lesions, reduce inflammation, and improve liver function. By focusing on high-protein foods and possibly incorporating amino acid supplements, dogs with SND can experience a better quality of life and longer periods between medical treatments.


For any dog dealing with skin disorders like SND, consulting a veterinarian and adjusting the diet to include adequate essential amino acids could be the key to long-term improvement and comfort.


Key Takeaways:

Amino acids like lysine, leucine, and valine are essential in treating Canine Superficial Necrolytic Dermatitis.

A balanced, high-protein diet is critical for dogs suffering from SND.

Essential amino acid therapy reduces the frequency of painful treatments and improves overall skin health.


Make sure to share this article with other pet owners and consult your veterinarian if your dog shows signs of Canine Superficial Necrolytic Dermatitis.

a dog chewing on a red rubber frisbee

Frequently Asked Questions

What is Canine Superficial Necrolytic Dermatitis?

Canine Superficial Necrolytic Dermatitis (SND), or hepatocutaneous syndrome, is a serious skin disorder in dogs characterized by painful, crusty lesions often found on the paws, muzzle, and genital areas. It is commonly associated with liver dysfunction or metabolic disturbances and is marked by deficiencies in essential amino acids, leading to a poor prognosis if untreated.

What are Amino Acids?

Amino acids are organic compounds that serve as the building blocks of proteins. There are 20 different amino acids, nine of which are essential and must be obtained through diet. Essential amino acids are crucial for various bodily functions, including tissue repair, immune response, and hormone production, and are particularly important for maintaining skin health in dogs.

How to Treat Canine Superficial Necrolytic Dermatitis?

Treating Canine Superficial Necrolytic Dermatitis typically involves a combination of amino acid therapy, a nutritionally balanced diet rich in protein, and supplementation with vitamins and minerals. A high-protein, home-cooked diet can promote skin health and reduce inflammation, while veterinary care ensures proper monitoring and adjustments to the treatment plan.

Does my Dog have Superficial Necrolytic Dermatitis?

Signs that your dog may have Superficial Necrolytic Dermatitis include thick, crusty lesions on the paws, muzzle, and genital areas, along with signs of discomfort such as excessive licking or chewing. Other symptoms may include hair loss and signs of liver dysfunction, such as increased thirst, lethargy, or a pot-bellied appearance. If you notice these symptoms, consult your veterinarian for a diagnosis.

How THRIVE Daily can help?

THRIVE Daily is a freeform amino acid supplement that ensures your dog receives essential nutrients in a highly absorbable form. This is particularly beneficial for dogs with Canine Superficial Necrolytic Dermatitis, as it supports skin repair, reduces inflammation, and improves overall metabolic function. Incorporating THRIVE Daily into your dog's routine can lead to better treatment outcomes and an improved quality of life.